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DCAF11 ligand 2

E3 ligase ligand

DCAF11 ligand 2 is an E3 ligase ligand that facilitates the recruitment of DCAF11. This compound is essential for the development of PROTACs, specifically for synthesizing the BRD4 degrader LGF308, which targets BRD4 for ubiquitination and proteasomal degradation. The ability to harness DCAF11 ligand 2 in research applications contributes significantly to the advancement of targeted protein degradation strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	24044-52-8
Applications	E3 ligase ligand
Formula	C₁₀H₆N₂O₄S
Molecular Weight	250.23
SMILES	O=C(N1)/C(SC1=O)=C/C2=CC([N+]([O-])=O)=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.