Fig. 1 · Structure
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DCB
mGluR5 Allosteric Modulator
DCB (3,3′-dichlorobenzaldazine) functions as a neutral allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5). It effectively inhibits the positive allosteric enhancement of mGluR5 activity. DCB serves as a valuable tool in research focused on modulating glutamatergic signaling pathways, with implications in understanding neurological disorders and related therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 6971-97-7 |
| Applications | mGluR5 Allosteric Modulator |
| Formula | C14H10Cl2N2 |
| Molecular Weight | 277.15 |
| SMILES | ClC1=CC(/C=N/N=C/C2=CC=CC(Cl)=C2)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.