Fig. 1 · Structure
Documents & Downloads
dCeMM1
RBM39 Degrader
dCeMM1 is a selective degrader of RBM39 that operates through the recruitment of the CRL4DCAF15 E3 ligase complex. This compound effectively reduces the protein levels of RBM39 in wild-type KBM7 cells, offering a potent tool for studying the role of RBM39 in cellular processes. dCeMM1's mechanism provides valuable insights for research applications in targeted protein degradation and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 118719-16-7 |
| Applications | RBM39 Degrader |
| Formula | C14H13BrN2O3S |
| Molecular Weight | 369.23 |
| SMILES | O=S(C1=CC=C(C)C=C1)(NN=CC2=CC(Br)=CC=C2O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.