Fig. 1 · Structure
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DCG-IV
Group II mGluRs Agonist
DCG-IV is a potent agonist of group II metabotropic glutamate receptors (mGluRs), displaying EC50 values of 0.35 μM for mGlu2R and 0.09 μM for mGlu3R. Additionally, it acts as a competitive antagonist at group I and group III mGluRs, with respective IC50 values of 389 μM and 22.5-630 μM. DCG-IV has demonstrated anticonvulsive and neuroprotective properties, making it valuable for research in neurobiology and pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 147782-19-2 |
| Applications | Group II mGluRs Agonist |
| Formula | C7H9NO6 |
| Molecular Weight | 203.15 |
| SMILES | O=C([C@H]1[C@H](C(O)=O)C1[C@H](N)C(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.