Fig. 1 · Structure
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DCZ5418
TRIP13 Inhibitor
DCZ5418 is a selective inhibitor of TRIP13, a protein involved in the regulation of the spindle assembly checkpoint. This compound demonstrates significant anti-multiple myeloma activity in both in vitro and in vivo models. DCZ5418 is valuable for studies exploring the mechanisms of cancer cell proliferation and the potential for targeted therapies in hematological malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2883709-99-5 |
| Applications | TRIP13 Inhibitor |
| Formula | C22H22N2O3 |
| Molecular Weight | 362.42 |
| SMILES | O=C(N1C2=CC=C(C=C2)CC3=CC=NC=C3)[C@@]4(C)[C@@]([C@@H]5CC[C@H]4O5)(C)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.