Fig. 1 · Structure
Documents & Downloads
DDO-3055
PHD2 Inhibitor
DDO-3055 is an orally active inhibitor of prolyl hydroxylase domain-containing protein 2 (PHD2), which plays a crucial role in regulating hypoxia-inducible factor (HIF) stability. It is primarily utilized in research related to anemia, particularly in the context of chronic kidney disease. The compound’s ability to modulate HIF levels makes it a valuable tool for investigating pathways associated with erythropoiesis and oxygen homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1842340-93-5 |
| Applications | PHD2 Inhibitor |
| Formula | C17H13ClN2O5 |
| Molecular Weight | 360.75 |
| SMILES | ClC1=CC=C(OCC#CC2=CC(O)=C(C(NCC(O)=O)=O)N=C2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.