DDR1/2 IN-4 is a selective dual inhibitor targeting DDR1 and DDR2 kinases, demonstrating a pKi of 8.6 for DDR1 and 8.2 for DDR2. This compound effectively inhibits the kinase activities of both DDR1 and DDR2, leading to a reduction in the release of MCP-1. DDR1/2 IN-4 is suitable for research applications focused on idiopathic pulmonary fibrosis and related cellular mechanisms.
DDR1/2 IN-4 is a selective dual inhibitor targeting DDR1 and DDR2 kinases, demonstrating a pKi of 8.6 for DDR1 and 8.2 for DDR2. This compound effectively inhibits the kinase activities of both DDR1 and DDR2, leading to a reduction in the release of MCP-1. DDR1/2 IN-4 is suitable for research applications focused on idiopathic pulmonary fibrosis and related cellular mechanisms.
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