Fig. 1 · Structure
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DDR1/2 inhibitor-2
DDR1/DDR2 Inhibitor
DDR1/2 inhibitor-2 is a selective inhibitor of the DDR1 and DDR2 receptor tyrosine kinases, demonstrating IC50 values of less than 100 nM. This compound is primarily utilized in research related to cancer and fibrotic diseases, providing insights into the role of these receptors in tumor progression and fibrosis. Its potent inhibitory effects make it a valuable tool for studying DDR signaling pathways and their contributions to disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2908756-11-4 |
| Applications | DDR1/DDR2 Inhibitor |
| Formula | C25H19F3N6O2 |
| Molecular Weight | 492.45 |
| SMILES | O=C(CN1C=CC2=C(C1=O)C(NC3=CC(C=NN4C)=C4C=C3)=CC=C2)NC5=CN=CC(C(F)(F)F)=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.