Fig. 1 · Structure

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DDR1/2 inhibitor-3

DDR1/2 Inhibitor

DDR1/2 inhibitor-3 is a selective inhibitor of discoidin domain receptor 1 and 2 (DDR1/2), exhibiting IC50 values of 9.4 nM and 20.4 nM, respectively. This compound is primarily utilized in anti-inflammatory research, targeting the DDR pathways involved in cellular responses to inflammation. Its potent inhibitory effects make it a valuable tool for elucidating the role of DDR receptors in various biological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2241813-33-0
Applications DDR1/2 Inhibitor
Formula C31H31F3N6O
Molecular Weight 560.61
SMILES
O=C(NC1=CC(C(F)(F)F)=CC(CN2CCN(C)CC2)=C1)C3=CC=C(C(C)C)C(C#CC4=CN=C5C=NC=CN54)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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