Fig. 1 · Structure

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DDR1-IN-8

DDR1/2 Inhibitor

DDR1-IN-8 is a potent dual inhibitor of DDR1 and DDR2, demonstrating IC50 values of 0.045 μM and 0.126 μM, respectively. This compound exhibits significant anti-tumor activity, making it a valuable tool for studies related to cancer research. DDR1-IN-8 can be utilized to explore the role of DDR signaling in tumor progression and therapeutics targeting the DDR pathway.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3038810-92-0
Applications DDR1/2 Inhibitor
Formula C23H24F3N5O2
Molecular Weight 459.46
SMILES
O=C(NCC1=CN(CC(N2CCN(CC2)C)=O)C3=C1C=C(F)C=C3)NC4=CC=C(C=C4F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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