Fig. 1 · Structure
Documents & Downloads
DDR2-IN-1
DDR2 Inhibitor
DDR2-IN-1 is a potent inhibitor of the Discoidin Domain Receptor 2 (DDR2) with an IC50 of 26 nM. This compound plays a significant role in research related to osteoarthritis by modulating collagen signaling pathways and potentially influencing cartilage degradation and repair. Its application in studying DDR2-mediated processes makes it a valuable tool for investigating therapeutic strategies in bone and joint diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1573053-23-2 |
| Applications | DDR2 Inhibitor |
| Formula | C27H32ClN5O4 |
| Molecular Weight | 526.03 |
| SMILES | O=C(C1=NC=CC(OC2=CC=C(CNC(NC3=CC(C)=C(Cl)C=C3OCCN(C)C)=O)C=C2C)=C1)NC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.