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Debrisoquin hydrobromide

TMPRSS2 Inhibitor

Debrisoquin hydrobromide is a TMPRSS2 inhibitor that plays a critical role in blocking SARS-CoV-2 entry into human lung cells through a TMPRSS2-dependent mechanism, exhibiting an IC50 of 22 μM. This compound serves as a valuable reagent for antiviral research, contributing to the understanding of viral entry processes and potential therapeutic strategies against SARS-CoV-2 infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1131-65-3
Applications	TMPRSS2 Inhibitor
Formula	C₁₀H₁₄BrN₃
Molecular Weight	256.14
Synonyms	Debrisoquine hydrobromide; Isocaramidine hydrobromide; Ro 5-3307/1 hydrobromide
SMILES	N=C(N1CC2=C(CC1)C=CC=C2)N.Br

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.