Fig. 1 · Structure
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Debrisoquin hydroiodide
TMPRSS2 Inhibitor
Debrisoquin hydroiodide is a potent inhibitor of the transmembrane serine protease 2 (TMPRSS2), blocking its role in the entry of SARS-CoV-2 into human lung cells. This compound is primarily utilized in antiviral research, providing valuable insights into viral mechanisms and potential therapeutic strategies targeting TMPRSS2. Its application in studies related to COVID-19 pathogenesis makes it an important tool for researchers focused on combating SARS-CoV-2.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1052540-65-4 |
| Applications | TMPRSS2 Inhibitor |
| Formula | C10H14IN3 |
| Molecular Weight | 303.14 |
| Synonyms | Debrisoquine hydroiodide; Isocaramidine hydroiodide; Ro 5-3307/1 hydroiodide |
| SMILES | N=C(N1CC2=C(CC1)C=CC=C2)N.I |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.