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Debrisoquin

TMPRSS2 Inhibitor

Debrisoquin, a TMPRSS2 inhibitor, effectively blocks the entry of SARS-CoV-2 into human lung cell lines in a TMPRSS2-dependent manner, with an IC50 of 22 µM. This compound is a valuable tool for antiviral research, particularly in understanding the molecular interactions involved in viral entry and potential therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1131-64-2
Applications	TMPRSS2 Inhibitor
Formula	C₁₀H₁₃N₃
Molecular Weight	175.23
Synonyms	Debrisoquine; Isocaramidine; Ro 5-3307/1
SMILES	NC(N1CCC2=C(C1)C=CC=C2)=N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.