Documents & Downloads

DEC-RVRK-CMK

CMK Inhibitor

DEC-RVRK-CMK is a peptide-based inhibitor of the CMK (chloromethylketone) class, specifically targeting the secreted soluble kexin (Kex2) with a Ki of 8.45 μM. Kexin (Kex2), a calcium-dependent transmembrane protease classified under the serine protease subtilisin family, plays an essential role in protein maturation processes in yeast. This compound is particularly useful for studying substrate selectivity and the differential binding interactions of Kex2 with various CMK inhibitors, highlighting the positional effects of amino acids such as lysine and arginine.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	534615-50-4
Applications	CMK Inhibitor
Formula	C₃₄H₆₆ClN₁₁O₅
Molecular Weight	744.41
Synonyms	Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
SMILES	[C@H](C(N[C@@H](CCCCN)C(CCl)=O)=O)(NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CCCNC(=N)N)=O)C(C)C)=O)CCCNC(=N)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.