Fig. 1 · Structure
Documents & Downloads
Decoglurant
mGluR2/mGluR3 NAM
Decoglurant is a negative allosteric modulator of metabotropic glutamate receptors 2 and 3 (mGluR2/mGluR3). It exhibits potential antidepressant properties, making it a valuable compound for research into mood disorders and neuropharmacology. Decoglurant is of interest for studies focused on the modulation of glutamatergic signaling pathways and the development of new therapeutic strategies for anxiety and depression-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 911115-16-7 |
| Applications | mGluR2/mGluR3 NAM |
| Formula | C21H11F6N5 |
| Molecular Weight | 447.34 |
| Synonyms | RO4995819 |
| SMILES | NC1=NC=C(C#CC2=C3N=C(C4=CC=C(C(F)(F)F)C=C4)C=C(C(F)(F)F)N3N=C2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.