Fig. 1 · Structure
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Decyclohexanamine-Exatecan
Camptothecin Derivative
Decyclohexanamine-Exatecan is a Camptothecin derivative that serves as an ADC cytotoxin. This compound exhibits potent cytotoxic activity through the inhibition of topoisomerase I, leading to disruption of DNA replication and transcription. It is utilized in research applications focused on cancer therapy and the development of antibody-drug conjugates.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2505045-51-0 |
| Applications | Camptothecin Derivative |
| Formula | C21H17FN2O4 |
| Molecular Weight | 380.37 |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(N3C(C(C(C3)=CC4=C5)=NC4=CC(F)=C5C)=C2)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.