Defactinib

Catalog No.: A21958
FAK inhibitor
Defactinib (VS-6063; PF-04554878) is a novel FAK inhibitor with potential antiangiogenic and antineoplastic activities.
Grouped product items
Product Name Price Stock Qty
Defactinib 5mg
Special Price $60.80 Regular Price $76.00
In stock
Defactinib 10mg
Special Price $104.00 Regular Price $130.00
In stock
Defactinib 50mg
Special Price $308.80 Regular Price $386.00
In stock
Defactinib 100mg
Special Price $618.40 Regular Price $773.00
In stock
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Biological Activity
Discription Defactinib (VS-6063; PF-04554878) is a novel FAK inhibitor with potential antiangiogenic and antineoplastic activities.
Product Information
Catalog Num A21958
Formula C20H21F3N8O3S
Molecular Weight 510.49
CAS Number 1073154-85-4
SMILES O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1
Synonyms VS-6063, VS 6063, VS6063; PF-04554878, PF04554878, PF04554878
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 5 mg/mL (9.79 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+50% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.95 mL 195.89 mL
0.5 mM 3.92 mL 19.59 mL 39.18 mL
1 mM 1.96 mL 9.79 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL
Useful Calculator

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