Deferasirox

Name: Deferasirox
Brand: Adooq Bioscience
SKU: A10293
Rating: 5 (2 reviews)

Catalog No.: A10293

Iron chelator

Adooq's Deferasirox has been cited by 2 publications

Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.

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Grouped product items
Size	Price	Stock
5mg	$35.00	In stock
10mg	$55.00	In stock
25mg	$70.00	In stock
50mg	$110.00	In stock
100mg	$165.00	In stock
500mg	$420.00	In stock
*10mM 1mL in DMSO**	$40.00	In stock
Bulk Size	Bulk Discount

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Research use only. We do not sell to patients.

Data Sheet SDS

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Adooq Products cited in reputable paper

Adooq's Deferasirox has been cited by 2 publications

Céline Moison, .et al. , Sci Adv, 2024, Mar 22;10(12):eadl4018 PMID: 38517966
Jamie L. Dombach, .et al. , PLoS Pathog, 2020, Dec; 16(12): e1009119 PMID: 33290418

Biological Activity

Description	Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.

Product Information

Catalog Num	A10293
Formula	C21H15N3O4
Molecular Weight	373.36
CAS Number	201530-41-8
SMILES	C1=C/C(=C\2/N/C(=C\3/C=CC=CC3=O)/N(N2)C4=CC=C(C=C4)C(=O)O)/C(=O)C=C1
Synonyms	ICL-670, ICL-670A, CGP-72670
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	64 mg/mL (171.42 mM)
	Water	Insoluble
	Ethanol	2 mg/mL
In vivo	5% DMSO+40% PEG 300+5%Tween 80 +50 % H2O	3.5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.78 mL	133.92 mL	267.84 mL
0.5 mM	5.36 mL	26.78 mL	53.57 mL
1 mM	2.68 mL	13.39 mL	26.78 mL
5 mM	0.54 mL	2.68 mL	5.36 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂