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|Storage||at -20°C 3 years Powder|
|Synonyms||ICL-670, ICL-670A, CGP-72670|
|Chemical Name||[4-[(3Z,5E)-3,5-bis(6-oxo-1-cyclohexa-2,4-dienylidene)-1,2,4-triazolidin-1-yl]benzoic acid|
|Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.|
|Solubility (25°C) *||In vitro||DMSO||74 mg/mL (198.2 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||2 mg/mL (5.35 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||26.78 mL||133.92 mL||267.84mL|
|0.5 mM||5.36 mL||26.78 mL||53.57 mL|
|1 mM||2.68 mL||13.39 mL||26.78 mL|
|5 mM||0.54 mL||2.68 mL||5.36 mL|
*The above data is based on the productmolecular weight 373.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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