Fig. 1 · Structure

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Dehydro Palonosetron

5-HT3 Receptor Antagonist

Dehydro Palonosetron is a potent and selective 5-HT3 receptor antagonist known for its oral activity. It effectively inhibits the 5-HT3 receptor without influencing the functions of 5-HT1, 5-HT2, or 5-HT4 receptors. This compound is widely utilized in research applications focusing on the management of nausea and vomiting, particularly in chemotherapy settings. Its specific targeting makes it a valuable tool for studies exploring serotonergic modulation in various physiological and pathological contexts.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 135729-56-5
Applications 5-HT3 Receptor Antagonist
Formula C19H22N2O
Molecular Weight 294.39
Synonyms RS 42358-197
SMILES
O=C1N([C@@H]2CN3CCC2CC3)C=C4C5=C1C=CC=C5CCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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