Fig. 1 · Structure
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Delocamten
Myosin Inhibitor
Delocamten is a selective inhibitor of cardiac myosin with an IC50 of 1.1 μM. It inhibits myosin-driven muscle contraction, making it a valuable tool for studying hypertrophic cardiomyopathy, left ventricular hypertrophy, and diastolic dysfunction. Delocamten is critical for research into the molecular mechanisms underlying cardiac muscle disorders and therapeutic interventions targeting these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2417411-02-8 |
| Applications | Myosin Inhibitor |
| Formula | C19H21F2N3O3 |
| Molecular Weight | 377.39 |
| SMILES | O=C1C2=C(NC(N1C3CCOCC3)=O)N[C@@H](C4=C(C=CC(C)=C4)F)[C@H](C2)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.