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Biological Activity
Demethoxydeacetoxypseudolaric acid B analog (Compound 13b) is semi-synthesized by efficient routines from Pseudolaric acid B. It has potent activities against HMEC-1, HL-60, A-549, MB-MDA-468, BEL-7402, HCT116, and Hela cells with IC50s ranging from 0.136 to 1.162 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.4 mL | 111.98 mL | 223.97 mL |
| 0.5 mM | 4.48 mL | 22.4 mL | 44.79 mL |
| 1 mM | 2.24 mL | 11.2 mL | 22.4 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
*The above data is based on the productmolecular weight 446.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18986 |
|---|---|
| CAS No. | 500736-17-4 |
| Formula | C24H30O8 |
| M. Wt | 446.49 |
| Purity | >98% |
| SMILES | CC(O[[email protected]]12[[email protected]@]3(CC=C(C(OCC)=O)CC2)C(O[[email protected]@](/C=C/C=C(C)/C(O)=O)(C)[[email protected]]1([H])CC3)=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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