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Demethyl-NSC682769

Ligand for Target Protein for PROTAC

Demethyl-NSC682769 functions as a ligand for target proteins in PROTAC applications. It plays a critical role in the development of PROTAC YAP degrader-1, facilitating targeted degradation of YAP protein. This compound is essential for researchers exploring the mechanism of targeted protein degradation and its therapeutic potential in cancer and other diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3058483-40-9
Applications	Ligand for Target Protein for PROTAC
Formula	C₂₆H₂₀N₂O₃
Molecular Weight	408.45
SMILES	OC1=CC=C(C=C1OC)C2=C(C(C3=CC=CC=C3N4)=NC(C5=CC=CC=C5)=C2)CC4=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.