Fig. 1 · Structure
Documents & Downloads
Deoxy-thalidomide-5-iodine
Thalidomide Analog
Deoxy-thalidomide-5-iodine is a Thalidomide analog that serves as a valuable tool in PROTAC (Proteolysis Targeting Chimeras) research. This compound is designed to facilitate targeted protein degradation by recruiting E3 ligases, enabling the selective elimination of specific proteins within cellular systems. Its unique structural modifications may enhance potency and efficacy in various biological assays, making it essential for advancing studies in targeted oncology and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2291364-01-5 |
| Applications | Thalidomide Analog |
| Formula | C13H11IN2O3 |
| Molecular Weight | 370.14 |
| SMILES | O=C(C(N(CC1=C2C=CC(I)=C1)C2=O)CC3)NC3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.