Documents & Downloads

Deoxy-thalidomide-OMe

Ligands for E3 Ligase

Deoxy-thalidomide-OMe is an E3 ligase ligand that plays a crucial role in targeted protein degradation mechanisms. This compound is utilized in the synthesis of PROTAC LRRK2 Degrader-4, facilitating research in the modulation of LRRK2 activity, which has implications in neurodegenerative diseases. Its ability to selectively engage with E3 ligases makes it a valuable tool for advancing studies in protein homeostasis and therapeutic development.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1061605-49-9
Applications	Ligands for E3 Ligase
Formula	C₁₄H₁₄N₂O₄
Molecular Weight	274.27
SMILES	COC1=CC=CC2=C1CN(C2=O)C3CCC(NC3=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.