Fig. 1 · Structure
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Deoxyribonuclease II
Endonuclease
Deoxyribonuclease II (DNase II) is an endonuclease that specifically hydrolyzes phosphodiester bonds in both native and denatured DNA, generating 3' phosphate and 5'-hydroxyl termini. Optimal activity is observed at acidic pH, making DNase II a valuable tool in biochemical research, particularly for studies involving DNA degradation and turnover. Its ability to cleave DNA makes it essential in applications such as nucleic acid purification and cellular apoptosis research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9025-64-3 |
| Applications | Endonuclease |
| Synonyms | DNase II |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.