Deracoxib-d3

Catalog No.: A32173
Stable Isotope
Deracoxib-d3 is a deuterated analog of Deracoxib, a selective COX-2 inhibitor. This compound primarily inhibits the COX-2 enzyme, effectively reducing prostaglandin production, and alleviates pain and inflammation, particularly following soft tissue surgeries in canine subjects. Additionally, Deracoxib has been shown to induce cell cycle arrest and apoptosis in tumor cells, demonstrating potential anti-tumor activity against conditions such as canine osteosarcoma, breast tumors, and bladder transitional cell carcinomas. As a stable isotope, Deracoxib-d3 is valuable in pharmacokinetic studies and biochemical research.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDeracoxib-d3 is a deuterated analog of Deracoxib, a selective COX-2 inhibitor. This compound primarily inhibits the COX-2 enzyme, effectively reducing prostaglandin production, and alleviates pain and inflammation, particularly following soft tissue surgeries in canine subjects. Additionally, Deracoxib has been shown to induce cell cycle arrest and apoptosis in tumor cells, demonstrating potential anti-tumor activity against conditions such as canine osteosarcoma, breast tumors, and bladder transitional cell carcinomas. As a stable isotope, Deracoxib-d3 is valuable in pharmacokinetic studies and biochemical research.
Product Information
Catalog NumA32173
FormulaC17H11D3F3N3O3S
Molecular Weight400.39
CAS Number2012598-48-8
SMILESO=S(C1=CC=C(N2N=C(C(F)F)C=C2C3=CC=C(OC([2H])([2H])[2H])C(F)=C3)C=C1)(N)=O
SynonymsSC 046-d3; SC 46-d3; SC 59046-d3
Useful Calculator

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