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Deracoxib-d4

Stable Isotope

Deracoxib-d4 is a deuterium-labeled derivative of Deracoxib, a selective COX-2 inhibitor primarily employed in veterinary medicine. By inhibiting the COX-2 enzyme, Deracoxib-d4 effectively reduces prostaglandin synthesis, thus controlling pain and inflammation following soft tissue surgeries in dogs. This compound demonstrates minimal COX-1 inhibition, lowering the likelihood of gastrointestinal complications. Additionally, Deracoxib-d4 exhibits anti-tumor properties, inducing cell cycle arrest and apoptosis in various canine tumors, including osteosarcoma and transitional cell carcinoma of the bladder.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1794780-24-7
Applications	Stable Isotope
Formula	C₁₇H₁₀D₄F₃N₃O₃S
Molecular Weight	401.40
Synonyms	SC 046-d4; SC 46-d4; SC 59046-d4
SMILES	[2H]C1=C([2H])C(S(=O)(N)=O)=C([2H])C([2H])=C1N2C(C3=CC(F)=C(OC)C=C3)=CC(C(F)F)=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.