Deracoxib-d4

Catalog No.: A33069
Stable Isotope
Deracoxib-d4 is a deuterium-labeled derivative of Deracoxib, a selective COX-2 inhibitor primarily employed in veterinary medicine. By inhibiting the COX-2 enzyme, Deracoxib-d4 effectively reduces prostaglandin synthesis, thus controlling pain and inflammation following soft tissue surgeries in dogs. This compound demonstrates minimal COX-1 inhibition, lowering the likelihood of gastrointestinal complications. Additionally, Deracoxib-d4 exhibits anti-tumor properties, inducing cell cycle arrest and apoptosis in various canine tumors, including osteosarcoma and transitional cell carcinoma of the bladder.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDeracoxib-d4 is a deuterium-labeled derivative of Deracoxib, a selective COX-2 inhibitor primarily employed in veterinary medicine. By inhibiting the COX-2 enzyme, Deracoxib-d4 effectively reduces prostaglandin synthesis, thus controlling pain and inflammation following soft tissue surgeries in dogs. This compound demonstrates minimal COX-1 inhibition, lowering the likelihood of gastrointestinal complications. Additionally, Deracoxib-d4 exhibits anti-tumor properties, inducing cell cycle arrest and apoptosis in various canine tumors, including osteosarcoma and transitional cell carcinoma of the bladder.
Product Information
Catalog NumA33069
FormulaC17H10D4F3N3O3S
Molecular Weight401.40
CAS Number1794780-24-7
SMILES[2H]C1=C([2H])C(S(=O)(N)=O)=C([2H])C([2H])=C1N2C(C3=CC(F)=C(OC)C=C3)=CC(C(F)F)=N2
SynonymsSC 046-d4; SC 46-d4; SC 59046-d4
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