Target & Activity
| Target | Activity | Value |
|---|---|---|
| A1R | Ki | 1 nM |
| Adenosine A3 receptor | Ki | 200 nM |
| A2AR | Ki | 398 nM |
Fig. 1 · Structure
Documents & Downloads
Derenofylline
Cat. No.
A21990
CAS
251945-92-3
adenosine A1 receptor antagonist
Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 251945-92-3 |
| Applications | adenosine A1 receptor antagonist |
| Formula | C18H20N4O |
| Molecular Weight | 308.38 |
| Synonyms | SLV 320 |
| SMILES | O[C@H]1CC[C@H](NC2=C3C(NC=C3)=NC(C4=CC=CC=C4)=N2)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.