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(Des-Glu5)-ACTH (1-24) (human, bovine, rat)

ACTH Analogue

(Des-Glu5)-ACTH (1-24) is an analogue of Adrenocorticotropic hormone (ACTH) that primarily targets the adrenal cortex to modulate endocrine functions. This polypeptide hormone plays a crucial role in stimulating cortisol and androgen synthesis from the adrenal glands. Researchers utilize this analogue in studies of stress response, adrenal function, and neuroendocrine signaling, providing insight into therapeutic targets for disorders related to cortisol dysregulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1815617-95-8
Applications	ACTH Analogue
Formula	C₁₃₁H₂₀₃N₃₉O₂₈S
Molecular Weight	2804.32
SMILES	CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.