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Desamino lenalidomide3,4-gpiperidine

Ligand for E3 Ligase

Desamino lenalidomide[3,4-g]piperidine is a ligand for the E3 ubiquitin ligase cereblon (CRBN), playing a critical role in targeted protein degradation. This compound facilitates the recruitment of the cereblon protein, enabling the design of bifunctional therapeutic molecules when linked to a target protein ligand through a suitable linker. It serves as a valuable tool in research applications focused on the modulation of protein homeostasis and therapeutic strategies against various diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2616539-63-8
Applications	Ligand for E3 Ligase
Formula	C₁₆H₁₇N₃O₃
Molecular Weight	299.33
SMILES	O=C1NC(=O)C(N2C(=O)C=3C=C4C(=CC3C2)CCNC4)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.