Desamino lenalidomide-4-Br-5-F is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be utilized to create PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its ability to modulate protein degradation makes it valuable in various research applications, including targeted protein elimination and the study of cellular mechanisms involving ubiquitin-proteasome pathways.
Desamino lenalidomide-4-Br-5-F is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be utilized to create PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its ability to modulate protein degradation makes it valuable in various research applications, including targeted protein elimination and the study of cellular mechanisms involving ubiquitin-proteasome pathways.
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