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Desamino lenalidomide-4-Br-6-acetonitrile

Ligand for E3 Ligase

Desamino lenalidomide-4-Br-6-acetonitrile is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of cereblon to target proteins. This compound can be utilized in the development of proteolysis-targeting chimeras (PROTACs) by connecting it to a target protein ligand through a suitable linker. Its application in targeted protein degradation research contributes to innovative therapeutic strategies in oncology and other areas of drug development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2438238-19-6
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₀BrN₃O₃
Molecular Weight	348.16
SMILES	N#CC=1C=C(Br)C2=C(C1)C(=O)N(C2)C3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.