Desamino lenalidomide-4-C-COOH is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein in targeted protein degradation applications. This compound can be conjugated to a target protein ligand through a linker, enabling the creation of Proteolysis Targeting Chimeras (PROTACs). Its utilization in research provides insights into protein regulation mechanisms and therapeutic strategies in diseases influenced by protein homeostasis.
Desamino lenalidomide-4-C-COOH is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein in targeted protein degradation applications. This compound can be conjugated to a target protein ligand through a linker, enabling the creation of Proteolysis Targeting Chimeras (PROTACs). Its utilization in research provides insights into protein regulation mechanisms and therapeutic strategies in diseases influenced by protein homeostasis.
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