Desamino lenalidomide-6-C-COOH is a ligand for E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein in biochemical assays. This compound can be conjugated with a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC), enabling targeted protein degradation. Its applications in drug development and cellular studies enhance understanding of protein regulation and therapeutic strategies.
Desamino lenalidomide-6-C-COOH is a ligand for E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein in biochemical assays. This compound can be conjugated with a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC), enabling targeted protein degradation. Its applications in drug development and cellular studies enhance understanding of protein regulation and therapeutic strategies.
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