Desamino lenalidomide-6-I functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This reagent can be conjugated with a target protein ligand through a suitable linker to create a PROTAC (Proteolysis Targeting Chimeras), which can enhance targeted protein degradation. It is valuable in research applications focused on ubiquitin-mediated proteolysis and drug development.
Desamino lenalidomide-6-I functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This reagent can be conjugated with a target protein ligand through a suitable linker to create a PROTAC (Proteolysis Targeting Chimeras), which can enhance targeted protein degradation. It is valuable in research applications focused on ubiquitin-mediated proteolysis and drug development.
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