Fig. 1 · Structure
Documents & Downloads
Desamino lenalidomide-7-OH
Ligand for E3 Ligase
Desamino lenalidomide-7-OH is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of cereblon to target proteins. This compound can be utilized in the design of PROTACs by linking it to a target protein ligand via a suitable linker. Its biological activity enables selective modulation of protein levels, making it a valuable tool in targeted protein degradation research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1416990-10-7 |
| Applications | Ligand for E3 Ligase |
| Formula | C13H12N2O4 |
| Molecular Weight | 260.25 |
| SMILES | O=C1NC(=O)C(N2C(=O)C=3C(O)=CC=CC3C2)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.