Desamino lenalidomide-7-OH

Catalog No.: A80516
Ligand for E3 Ligase
Desamino lenalidomide-7-OH is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of cereblon to target proteins. This compound can be utilized in the design of PROTACs by linking it to a target protein ligand via a suitable linker. Its biological activity enables selective modulation of protein levels, making it a valuable tool in targeted protein degradation research applications.
Grouped product items
Size Price Stock Qty
50mg
$45.00
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100mg
$50.00
In stock
250mg
$80.00
In stock
500mg
$115.00
In stock
1g
$170.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDesamino lenalidomide-7-OH is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of cereblon to target proteins. This compound can be utilized in the design of PROTACs by linking it to a target protein ligand via a suitable linker. Its biological activity enables selective modulation of protein levels, making it a valuable tool in targeted protein degradation research applications.
Product Information
Catalog NumA80516
FormulaC13H12N2O4
Molecular Weight260.25
CAS Number1416990-10-7
SMILESO=C1NC(=O)C(N2C(=O)C=3C(O)=CC=CC3C2)CC1
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