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Desamino lenalidomide-Bpin

Ligand for E3 Ligase

Desamino lenalidomide-Bpin is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this critical protein for targeted protein degradation applications. Its chemical structure enables the conjugation of Desamino lenalidomide-Bpin to a target protein ligand via a linker, forming a proteolysis-targeting chimera (PROTAC). This compound is essential for research in areas such as targeted therapy and degradation of disease-related proteins.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2698398-71-7
Applications	Ligand for E3 Ligase
Formula	C₁₉H₂₃BN₂O₅
Molecular Weight	370.21
SMILES	O=C1C2=CC(=CC=C2CN1C3C(=O)NC(=O)CC3)B4OC(C)(C)C(O4)(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.