Desamino lenalidomide-CH2NH2 hydrochloride functions as a ligand for the E3 ubiquitin ligase protein cereblon (CRBN). This compound is instrumental in the targeted recruitment of cereblon, facilitating the development of protein-targeted degradation strategies. It can be conjugated with a target protein ligand through a suitable linker to create a proteolysis-targeting chimera (PROTAC), thereby advancing research in protein degradation and targeted therapies.
Desamino lenalidomide-CH2NH2 hydrochloride functions as a ligand for the E3 ubiquitin ligase protein cereblon (CRBN). This compound is instrumental in the targeted recruitment of cereblon, facilitating the development of protein-targeted degradation strategies. It can be conjugated with a target protein ligand through a suitable linker to create a proteolysis-targeting chimera (PROTAC), thereby advancing research in protein degradation and targeted therapies.
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