Fig. 1 · Structure

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Desamino lenalidomide-cyano

Ligand for E3 Ligase

Desamino lenalidomide-cyano is a ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound is utilized to recruit the cereblon protein, enabling targeted protein degradation. Desamino lenalidomide-cyano can be conjugated with a target protein ligand through a linker to create a PROTAC, facilitating innovative research in targeted therapeutics and protein regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2639386-82-4
Applications Ligand for E3 Ligase
Formula C14H11N3O3
Molecular Weight 269.26
SMILES
N#CC1=CC=C2C(=C1)C(=O)N(C2)C3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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