Desamino lenalidomide-ethynyl is an E3 ubiquitin ligase cereblon (CRBN) ligand that effectively recruits the cereblon protein. This compound can be conjugated with a target protein ligand through a linker to generate a PROTAC, facilitating targeted protein degradation for research applications. Its unique mechanism of action enables studies in protein homeostasis and therapeutic interventions in cancer and other diseases.
Desamino lenalidomide-ethynyl is an E3 ubiquitin ligase cereblon (CRBN) ligand that effectively recruits the cereblon protein. This compound can be conjugated with a target protein ligand through a linker to generate a PROTAC, facilitating targeted protein degradation for research applications. Its unique mechanism of action enables studies in protein homeostasis and therapeutic interventions in cancer and other diseases.
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