Fig. 1 · Structure

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Desethyl chloroquine-d5

Stable Isotope

Desethyl chloroquine-d5 is a deuterium-labeled form of Desethyl chloroquine, a significant metabolite of chloroquine. It functions as an inhibitor of autophagy and toll-like receptors (TLRs), thereby influencing immune response pathways. This compound exhibits antiplasmodic activity, making it valuable for research in malaria and related fields. Its stable isotope labeling enhances its utility in pharmacokinetic studies and metabolic tracking.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1261392-69-1
Applications Stable Isotope
Formula C16H17D5ClN3
Molecular Weight 296.85
SMILES
CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCNC([2H])([2H])C([2H])([2H])[2H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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