Desethyl chloroquine-d5

Catalog No.: A35407
Stable Isotope
Desethyl chloroquine-d5 is a deuterium-labeled form of Desethyl chloroquine, a significant metabolite of chloroquine. It functions as an inhibitor of autophagy and toll-like receptors (TLRs), thereby influencing immune response pathways. This compound exhibits antiplasmodic activity, making it valuable for research in malaria and related fields. Its stable isotope labeling enhances its utility in pharmacokinetic studies and metabolic tracking.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDesethyl chloroquine-d5 is a deuterium-labeled form of Desethyl chloroquine, a significant metabolite of chloroquine. It functions as an inhibitor of autophagy and toll-like receptors (TLRs), thereby influencing immune response pathways. This compound exhibits antiplasmodic activity, making it valuable for research in malaria and related fields. Its stable isotope labeling enhances its utility in pharmacokinetic studies and metabolic tracking.
Product Information
Catalog NumA35407
FormulaC16H17D5ClN3
Molecular Weight296.85
CAS Number1261392-69-1
SMILESCC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCNC([2H])([2H])C([2H])([2H])[2H]
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