Fig. 1 · Structure
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Desethylamiodarone
Antiarrhythmic Compound
Desethylamiodarone is an N-deethylated metabolite of the antiarrhythmic agent Amiodarone, primarily targeting ion channels involved in cardiac rhythm regulation. This compound exhibits notable antiarrhythmic activity and is also capable of inducing apoptosis in cancer cells. Desethylamiodarone is utilized in research focused on cardiac electrophysiology and cancer therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 83409-32-9 |
| Applications | Antiarrhythmic Compound |
| Formula | C23H25I2NO3 |
| Molecular Weight | 617.26 |
| Synonyms | N-Deethylamiodarone; LB 33020 |
| SMILES | O=C(C1=CC(I)=C(C(I)=C1)OCCNCC)C2=C(OC3=CC=CC=C23)CCCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.