Documents & Downloads

Deucravacitinib analog 1

TYK2 Allosteric Ligand

Deucravacitinib analog 1 is an allosteric ligand targeting the TYK2 kinase. It binds specifically to the JH2 domain of TYK2, providing a valuable scaffold for the development of PROTAC degraders aimed at this target. This compound is significant for research applications in conditions such as psoriasis and cancer, facilitating studies on TYK2's role in these diseases.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1609529-70-5
Applications	TYK2 Allosteric Ligand
Formula	C₂₇H₂₆FN₇O₃
Molecular Weight	515.54
SMILES	O=C(C1=CC=CC(NC2=CC(NC3=CC(C)=C(F)C=N3)=NC=C2C(NC)=O)=C1OC)NCC4=CC=CC=N4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.