Fig. 1 · Structure
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Deulorlatinib
Stable Isotope
Deulorlatinib is a deuterated derivative of Lorlatinib, functioning as a potent inhibitor of tyrosine kinases. It exhibits significant biological activity in targeting ALK-positive advanced non-small cell lung cancer (NSCLC), making it a valuable reagent for cancer research. This compound can be utilized to study the mechanistic pathways in oncogenic signaling and the therapeutic potential in NSCLC treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2131126-33-3 |
| Applications | Stable Isotope |
| Formula | C21H16D3FN6O2 |
| Molecular Weight | 409.43 |
| Synonyms | PF-06463922-d3-1 |
| SMILES | N#CC1=C2C3=CN=C(N)C(O[C@@H](C4=CC(F)=CC=C4C(N(CC2=NN1C([2H])([2H])[2H])C)=O)C)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.