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Deulorlatinib

Catalog No.: B12228
Stable Isotope
Deulorlatinib is a deuterated derivative of Lorlatinib, functioning as a potent inhibitor of tyrosine kinases. It exhibits significant biological activity in targeting ALK-positive advanced non-small cell lung cancer (NSCLC), making it a valuable reagent for cancer research. This compound can be utilized to study the mechanistic pathways in oncogenic signaling and the therapeutic potential in NSCLC treatment.
Deulorlatinib 2131126-33-3 Stable Isotope
Grouped product items
Size Price Stock Qty
100µg
$615.00
In stock
1mg
$1,840.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDeulorlatinib is a deuterated derivative of Lorlatinib, functioning as a potent inhibitor of tyrosine kinases. It exhibits significant biological activity in targeting ALK-positive advanced non-small cell lung cancer (NSCLC), making it a valuable reagent for cancer research. This compound can be utilized to study the mechanistic pathways in oncogenic signaling and the therapeutic potential in NSCLC treatment.
Product Information
Catalog NumB12228
FormulaC21H16D3FN6O2
Molecular Weight409.43
CAS Number2131126-33-3
SMILESN#CC1=C2C3=CN=C(N)C(O[C@@H](C4=CC(F)=CC=C4C(N(CC2=NN1C([2H])([2H])[2H])C)=O)C)=C3
SynonymsPF-06463922-d3-1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Isotope-Labeled Compounds