Deupirfenidone-d3 is a deuterium-labeled analog of Pirfenidone, a well-known antifibrotic agent that inhibits the production of pro-inflammatory cytokines CCL2 and CCL12 in fibrocyte cells. This compound demonstrates significant growth-inhibitory effects and reduces TGF-β2 protein levels in human glioma cell lines, highlighting its potential in cancer research. Additionally, Deupirfenidone-d3 exhibits anti-inflammatory properties, making it valuable for studies investigating fibrotic diseases and related conditions.
Deupirfenidone-d3 is a deuterium-labeled analog of Pirfenidone, a well-known antifibrotic agent that inhibits the production of pro-inflammatory cytokines CCL2 and CCL12 in fibrocyte cells. This compound demonstrates significant growth-inhibitory effects and reduces TGF-β2 protein levels in human glioma cell lines, highlighting its potential in cancer research. Additionally, Deupirfenidone-d3 exhibits anti-inflammatory properties, making it valuable for studies investigating fibrotic diseases and related conditions.
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