Fig. 1 · Structure

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Dexnafenodone hydrochloride

Antidepressant Compound

Dexnafenodone hydrochloride, also known as (S)-Nafenodone, is a selective inhibitor of synaptosomal noradrenaline uptake, demonstrating its potential as an antidepressant. This compound exhibits robust biological activity by effectively enhancing noradrenaline levels in the synaptic cleft while exerting weaker effects on serotonin and negligible effects on dopamine transport. It serves as a valuable tool in research exploring mood disorders and neurochemistry.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 94096-42-1
Applications Antidepressant Compound
Formula C20H24ClNO
Molecular Weight 329.86
Synonyms (S)-Nafenodone; LU-43706
SMILES
O=C1[C@](C2=CC=CC=C2)(CCN(C)C)CCC3=C1C=CC=C3.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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