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DGK-IN-10

DGK Inhibitor

DGK-IN-10 is a potent diacylglycerol kinase (DGK) inhibitor, demonstrating IC50 values of ≤ 10 nM against both DGKα and DGKζ isoforms. This compound exhibits significant inhibitory activity, making it a valuable tool in research related to various diseases, including cancer. Its specificity for DGK isoforms allows for detailed investigations into the role of DGK in cellular signaling pathways and disease mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3075645-89-2
Applications	DGK Inhibitor
Formula	C₂₈H₃₇F₃N₆O₂
Molecular Weight	546.63
SMILES	O=C(N1C)N=C(N2C[C@H](N(C[C@@H]2C)[C@H](C3=CC=C(C=C3)C(F)(F)F)C)CC)C(N=C4C)=C1N4C[C@@H]5CCCO5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.