Fig. 1 · Structure

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DGK-IN-11

DGK Inhibitor

DGK-IN-11 is a potent diacylglycerol kinase (DGK) inhibitor, specifically targeting DGKα and DGKγ. This compound effectively modulates intracellular diacylglycerol levels, leading to enhanced T cell activation, increased cytokine production, and improved cell proliferation. DGK-IN-11 is a valuable tool for investigating its potential applications in cancer research.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3023735-36-3
Applications DGK Inhibitor
Formula C29H31F2N9O
Molecular Weight 559.61
SMILES
FC(C=C1)=CC=C1C(C2=CC=C(C=C2)F)N3[C@H](C)CN(C4=NC5=NN=CN5C6=C4N=NN6C[C@@H]7OCCC7)[C@@H](C)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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