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DGK-IN-8

DGK Inhibitor

DGK-IN-8 is a specific inhibitor targeting diacylglycerol kinase (DGK) isoforms, including DGKα and DGKζ, with an IC50 value of ≤ 20 nM. This potent inhibitor is utilized in cancer research to investigate the role of DGK signaling in tumor growth and progression, providing insights into potential therapeutic strategies. Researchers can leverage DGK-IN-8 to explore the modulation of cellular signaling pathways influenced by diacylglycerol metabolism.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3039488-69-9
Applications	DGK Inhibitor
Formula	C₃₅H₃₇F₆N₅O
Molecular Weight	657.69
SMILES	FC(F)(C1=C(N2CC3(CCC2)CCN(CC3)CC4CC4)C(/C=C(C5=NC(N6CC(F)(C6)F)=CN=C5)\F)=CC=C1OC7=CC=CC=C7)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.